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Small Mammals

  • Dexmedetomidine is a sedative/tranquilizer used primarily in cats and dogs as a pre-medication injection for anesthesia or for chemical restraint. It is also used orally in dogs for short-term anxiety management. The most common side effect is a low heart rate. Dexmedetomidine should not be used in patients with severe heart liver or kidney disease. It should be used cautiously in young, old, or weak animals. Consult your veterinary office immediately if you suspect a negative reaction or overdose.

  • Diazepam is given by mouth, injection, or into the rectum and is used off label to treat anxiety, seizures, tense muscles, or decreased appetite. Give as directed by your veterinarian. Side effects include sleepiness, increased appetite, incoordination, weakness, agitation, drooling, and aggression. Do not give to cats by mouth, and do not use in pets that are allergic to it or other benzodiazepines, or in pets with severe liver disease. If a negative reaction occurs, please call your veterinary office.

  • Diazoxide is given by mouth and is used off label to treat low blood sugar associated with insulin-producing tumors of the pancreas. Give as directed by your veterinarian. Common side effects include drooling, lack of appetite, vomiting, and diarrhea. Do not use in pets that are allergic to it or thiazide diuretics, or in pets with low blood sugar due to anything other than a tumor. If a negative reaction occurs, please call your veterinary office.

  • Diphenhydramine is given by mouth or as an injection and is used on and off label to treat allergic reactions, motion sickness, and to induce sedation. Side effects include sleepiness, and less commonly dry mouth and gastrointestinal upset. Diphenhydramine should not be used in pets that are allergic to this medication and should be used cautiously in pets with glaucoma, enlarged prostate, thyroid or heart disease, or are lactating. If a negative reaction occurs, please call your veterinary office.

  • Common conditions of pet ferrets include diarrhea, intestinal foreign bodies, parasites, heart disease, and various tumors. This handout outlines the causes, clinical signs, and treatment options for each of these conditions. Any variation from normal should be a cause for concern and should be immediately evaluated by your veterinarian.

  • Common conditions of pet rabbits include upper respiratory tract infections, internal and external parasites, dental disease, GI stasis, uterine problems, and pododermatitis. Upper respiratory infections are often caused by bacteria including Pasteurella multocida. Rabbits can become infected with various intestinal parasites, as well as external parasites such as ear and fur mites, fleas, and occasionally ticks. Rabbits’ teeth are continuously growing but chewing food, as well as chewing on wooden blocks, branches, and toys, helps them wear their teeth down at a rate equal to their growth. Occasionally, tooth or jaw trauma or disease causes misalignment of the upper and lower jaws and overgrowth of teeth results. Regular yearly check-ups enables early diagnosis and treatment of some rabbit diseases. Whenever a rabbit stops eating, for whatever reason, it is important to take her to see your veterinarian immediately for an evaluation.

  • Common conditions of pet rodents include respiratory diseases, gastrointestinal problems, dental problems, and tumors. Signs of respiratory disease in rodents include nasal and/or ocular discharge in mild infections, and wheezing, coughing, and open-mouth breathing in severe infections. Gastrointestinal disease, including diarrhea from various causes and gastrointestinal stasis is common in pet rodents. All rodents have teeth that grow continuously throughout their lives. Occasionally, these teeth grow too long and cut into the gums, causing pain, or prevent the mouth from closing properly, which often makes the pet stop eating. Just as in people, cancer is often seen in pet rodents, especially mammary (breast) tumors in rats and mice. Rodents with signs of respiratory or GI disease or evidence of a tumor should be seen by a veterinarian who can properly diagnose and treat the underlying condition.

  • Doxycycline is an antibiotic given by mouth in the form of a tablet, capsule, or liquid, used off label to treat certain infections. Common side effects include stomach upset, sun sensitivity, and increases in liver enzymes. Serious side effects include liver failure, seizures, and trouble swallowing. Do not use in pregnant pets, and use cautiously in pets with liver disease or in young pets. If a negative reaction occurs, please call your veterinary office.

  • The ear mite is a surface mite that lives on cats, dogs, rabbits, and ferrets. It is usually found in the ear canal but it can also live on the skin surface. Mites are barely visible to the naked eye. Clinical signs of infestation vary in severity and may include ear irritation, leading to scratching at the ears or head shaking, dark waxy or crusty discharge from the ear, areas of hair loss resulting from self-trauma, a crusted rash around or in the ear, and an aural hematoma. Your veterinarian will advise you about which insecticidal products are suitable. Your veterinarian may want to re-examine your pet to ensure that the mites have been eliminated after the initial treatment has been performed.

  • Enalapril is used on and off label and is given by mouth or injection to treat heart failure, high blood pressure, chronic kidney disease, or proteinuria. Common side effects include loss of appetite, vomiting, diarrhea, and tiredness. Do not use in pets that are allergic to it, have an acute kidney injury, or have certain heart conditions. If a negative reaction occurs, please call your veterinary office.